Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice

Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan and healthy aging in mice would have greater impact than a...

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Detalles Bibliográficos
Autores principales: Jiang, Zhou, Wang, Juan, Imai, Denise, Snider, Tim, Klug, Jenna, Mangalindan, Ruby, Morton, John, Zhu, Lida, Salmon, Adam B., Wezeman, Jackson, Hu, Jiayi, Menon, Vinal, Marka, Nicholas, Neidernhofer, Laura, Ladiges, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067553/
https://www.ncbi.nlm.nih.gov/pubmed/35508491
http://dx.doi.org/10.1038/s41598-022-11229-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067553/
https://www.ncbi.nlm.nih.gov/pubmed/35508491
http://dx.doi.org/10.1038/s41598-022-11229-1

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