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Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice
Pharmaceutical intervention of aging requires targeting multiple pathways, thus there is rationale to test combinations of drugs targeting different but overlapping processes. In order to determine if combining drugs shown to extend lifespan and healthy aging in mice would have greater impact than a...
Autores principales: | Jiang, Zhou, Wang, Juan, Imai, Denise, Snider, Tim, Klug, Jenna, Mangalindan, Ruby, Morton, John, Zhu, Lida, Salmon, Adam B., Wezeman, Jackson, Hu, Jiayi, Menon, Vinal, Marka, Nicholas, Neidernhofer, Laura, Ladiges, Warren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067553/ https://www.ncbi.nlm.nih.gov/pubmed/35508491 http://dx.doi.org/10.1038/s41598-022-11229-1 |
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