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Stereodivergent synthesis of enantioenriched azepino[3,4,5-cd]-indoles via cooperative Cu/Ir-catalyzed asymmetric allylic alkylation and intramolecular Friedel–Crafts reaction

The development of enantioselective annulation reactions using readily available substrates for the construction of structurally and stereochemically diverse heterocycles is a compelling topic in diversity-oriented synthesis. Herein, we report efficient catalytic asymmetric formal 1,3-dipolar (3 + 4...

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Detalles Bibliográficos
Autores principales: Xiao, Lu, Li, Bo, Xiao, Fan, Fu, Cong, Wei, Liang, Dang, Yanfeng, Dong, Xiu-Qin, Wang, Chun-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067570/
https://www.ncbi.nlm.nih.gov/pubmed/35655885
http://dx.doi.org/10.1039/d1sc07271d