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Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation

Better understanding the mechanism of cisplatin-induced ototoxicity is of great significance for clinical prevention and treatment of cisplatin-related hearing loss. However, the mechanism of cisplatin-induced inflammatory response in cochlear stria vascularis and the mechanism of marginal cell (MC)...

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Detalles Bibliográficos
Autores principales: Yu, Wenting, Zong, Shimin, Zhou, Peng, Wei, Jiahui, Wang, Enhao, Ming, Ruijie, Xiao, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067579/
https://www.ncbi.nlm.nih.gov/pubmed/35529876
http://dx.doi.org/10.3389/fimmu.2022.823439