Stronger together for in-cell translation: natural and unnatural base modified mRNA

The preparation of highly modified mRNAs and visualization of their cellular distribution are challenging. We report in-cell application of in vitro transcribed mRNA containing natural base modifications and site-specifically introduced artificial nucleotides. Click chemistry on mRNA allows visualiz...

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Detalles Bibliográficos
Autores principales: Bornewasser, Lisa, Domnick, Christof, Kath-Schorr, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067582/
https://www.ncbi.nlm.nih.gov/pubmed/35655897
http://dx.doi.org/10.1039/d2sc00670g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067582/
https://www.ncbi.nlm.nih.gov/pubmed/35655897
http://dx.doi.org/10.1039/d2sc00670g

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