Biomimetic mimicry of formaldehyde-induced DNA–protein crosslinks in the confined space of a metal–organic framework

DNA–protein crosslinks (DPCs) are highly toxic DNA lesions induced by crosslinking agents such as formaldehyde (HCHO). Building artificial models to simulate the crosslinking process would advance our understanding of the underlying mechanisms and therefore develop coping strategies accordingly. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Yu-Bai, Luo, Dong, Xiong, Xiao, Huang, Yong-Liang, Xie, Mo, Lu, Weigang, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067591/
https://www.ncbi.nlm.nih.gov/pubmed/35655868
http://dx.doi.org/10.1039/d2sc00188h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067591/
https://www.ncbi.nlm.nih.gov/pubmed/35655868
http://dx.doi.org/10.1039/d2sc00188h

Ejemplares similares