Orphan Nuclear Receptor NR4A2 Is Constitutively Expressed in Cartilage and Upregulated in Inflamed Synovium From hTNF-Alpha Transgenic Mice

Orphan nuclear receptor 4A2 (NR4A2/Nurr1) is a constitutively active transcription factor with potential roles in the onset and progression of inflammatory arthropathies. NR4A2 is overexpressed in synovium and cartilage from individuals with rheumatoid arthritis (RA), psoriatic arthritis, and osteoa...

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Detalles Bibliográficos
Autores principales: Lilley, Cullen M., Alarcon, Andrea, Ngo, My-Huyen, Araujo, Jackeline S., Marrero, Luis, Mix, Kimberlee S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067626/
https://www.ncbi.nlm.nih.gov/pubmed/35529439
http://dx.doi.org/10.3389/fphar.2022.835697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067626/
https://www.ncbi.nlm.nih.gov/pubmed/35529439
http://dx.doi.org/10.3389/fphar.2022.835697

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