Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure

Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at the enhancer region of the activity-regulated cytoskeleton-associated protein (Arc) immediate-early gene, known as...

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Detalles Bibliográficos
Autores principales: Bohnsack, John Peyton, Zhang, Huaibo, Wandling, Gabriela M., He, Donghong, Kyzar, Evan J., Lasek, Amy W., Pandey, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067919/
https://www.ncbi.nlm.nih.gov/pubmed/35507645
http://dx.doi.org/10.1126/sciadv.abn2748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067919/
https://www.ncbi.nlm.nih.gov/pubmed/35507645
http://dx.doi.org/10.1126/sciadv.abn2748

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