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MiR-98-5p/IGF2 Axis Influence Herceptin Sensitivity through IGF1R/HER2 Heterodimer Formation and AKT/mTOR Signal Pathway in HER2 Positive Breast Cancer
BACKGROUND AND AIM: IGF1R and HER2 are both members of the growth factor receptor family which is known to play a different role in breast cancer. However, correlation between IGF1R and HER2 has created a controversial situation that need to be fully delineated in development of Herceptin resistance...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
West Asia Organization for Cancer Prevention
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068184/ https://www.ncbi.nlm.nih.gov/pubmed/34837929 http://dx.doi.org/10.31557/APJCP.2021.22.11.3693 |