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MiR-98-5p/IGF2 Axis Influence Herceptin Sensitivity through IGF1R/HER2 Heterodimer Formation and AKT/mTOR Signal Pathway in HER2 Positive Breast Cancer

BACKGROUND AND AIM: IGF1R and HER2 are both members of the growth factor receptor family which is known to play a different role in breast cancer. However, correlation between IGF1R and HER2 has created a controversial situation that need to be fully delineated in development of Herceptin resistance...

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Detalles Bibliográficos
Autores principales:	Zhang, Mingliang, Li, Zhixiang, Liu, Xianfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068184/ https://www.ncbi.nlm.nih.gov/pubmed/34837929 http://dx.doi.org/10.31557/APJCP.2021.22.11.3693

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