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Boosting targeted genome editing using the hei-tag

Precise, targeted genome editing by CRISPR/Cas9 is key for basic research and translational approaches in model and non-model systems. While active in all species tested so far, editing efficiencies still leave room for improvement. The bacterial Cas9 needs to be efficiently shuttled into the nucleu...

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Detalles Bibliográficos
Autores principales: Thumberger, Thomas, Tavhelidse-Suck, Tinatini, Gutierrez-Triana, Jose Arturo, Cornean, Alex, Medert, Rebekka, Welz, Bettina, Freichel, Marc, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068219/
https://www.ncbi.nlm.nih.gov/pubmed/35333175
http://dx.doi.org/10.7554/eLife.70558