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Soft repression: Subtle transcriptional regulation with global impact

Pleiotropically acting eukaryotic corepressors such as retinoblastoma and SIN3 have been found to physically interact with many widely expressed “housekeeping” genes. Evidence suggests that their roles at these loci are not to provide binary on/off switches, as is observed at many highly cell-type s...

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Detalles Bibliográficos
Autores principales: Mitra, Anindita, Raicu, Ana-Maria, Hickey, Stephanie L., Pile, Lori A., Arnosti, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068271/
https://www.ncbi.nlm.nih.gov/pubmed/33215731
http://dx.doi.org/10.1002/bies.202000231