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MDL-800, the SIRT6 Activator, Suppresses Inflammation via the NF-κB Pathway and Promotes Angiogenesis to Accelerate Cutaneous Wound Healing in Mice

Sirtuin 6 (SIRT6) is an NAD(+)-dependent deacetylase belonging to the sirtuin family. It has been shown to participate in wound healing and some inflammation-related disorders. However, the effect of MDL-800, a highly efficient and selective SIRT6 activator, on wound healing and inflammation has not...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaoqi, Yao, Zhe, Wang, Kangyan, Lou, Lihua, Xue, Kaikai, Chen, Jinghao, Zhang, Guojian, Zhang, Yu, Du, Jiqing, Lin, Cai, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068290/
https://www.ncbi.nlm.nih.gov/pubmed/35528512
http://dx.doi.org/10.1155/2022/1619651