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miR-21 Regulates Immune Balance Mediated by Th17/Treg in Peripheral Blood of Septic Rats during the Early Phase through Apoptosis Pathway

OBJECTIVE: To study the mechanism by which miR-21 regulates the differentiation and function of Th17/Treg cells in sepsis. METHODS: A rat model with sepsis was made by cecal ligation and puncture (CLP). Then, some of the septic rats were transfected with miR-21 mimic or inhibitor by liposome. At 48 ...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Zou, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068307/
https://www.ncbi.nlm.nih.gov/pubmed/35528843
http://dx.doi.org/10.1155/2022/9948229