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Organocatalytic stereoselective cyanosilylation of small ketones

Enzymatic stereoselectivity has typically been unrivalled by most chemical catalysts, especially in the conversion of small substrates. According to the ‘lock-and-key theory’(1,2), enzymes have confined active sites to accommodate their specific reacting substrates, a feature that is typically absen...

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Detalles Bibliográficos
Autores principales: Zhou, Hui, Zhou, Yu, Bae, Han Yong, Leutzsch, Markus, Li, Yihang, De, Chandra Kanta, Cheng, Gui-Juan, List, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068509/
https://www.ncbi.nlm.nih.gov/pubmed/35508776
http://dx.doi.org/10.1038/s41586-022-04531-5