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The effect of erythromycin and clarithromycin versus azithromycin on serum valproate concentration
INTRODUCTION: Unlike azithromycin, erythromycin and clarithromycin strongly inhibit CYP450, which metabolizes valproic acid. The aim of this study was to evaluate the impact of macrolide administration on serum valproate trough levels. METHODS: This retrospective cohort study included hospitalized a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068565/ https://www.ncbi.nlm.nih.gov/pubmed/35527827 http://dx.doi.org/10.1016/j.jsps.2022.02.004 |