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Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice

BACKGROUND: Previous studies showed inconsistent Results of the effects of dipeptidyl peptidase (DPP)-IV inhibitors on syngeneic mouse islet transplantation. We hypothesized that the implanted islet numbers are critical for the effects of DPP-IV inhibitors on the outcomes of transplantation. METHODS...

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Detalles Bibliográficos
Autores principales: Juang, Jyuhn-Huarng, Chen, Chen-Yi, Kao, Chen-Wei, Huang, Yu-Wen, Chiu, Tai-Yu, Chen, Chiung-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068567/
https://www.ncbi.nlm.nih.gov/pubmed/35300943
http://dx.doi.org/10.1016/j.bj.2020.10.002