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Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development

NR2E3 is an orphan nuclear receptor whose loss-of-function causes abnormal retinal photoreceptor development and degeneration. However, despite that many nuclear receptors are regulated by binding of small molecule ligands, biological small molecule ligands regulating NR2E3 have not been identified....

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Detalles Bibliográficos
Autores principales: Connor, Blaine, Titialii-Torres, Kayla, Rockenhaus, Abigail E., Passamonte, Samuel, Morris, Ann C., Lee, Young-Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068610/
https://www.ncbi.nlm.nih.gov/pubmed/35508617
http://dx.doi.org/10.1038/s41598-022-11502-3