PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress

The presence of ERG gene fusion; from developing prostatic intraepithelial neoplasia (PIN) lesions to hormone resistant high grade prostate cancer (PCa) dictates disease progression, altered androgen metabolism, proliferation and metastasis(1–3). ERG driven transcriptional landscape may provide pro-...

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Detalles Bibliográficos
Autores principales: Dhara, Aiindrila, Aier, Imlimaong, Paladhi, Ankush, Varadwaj, Pritish Kumar, Hira, Sumit Kumar, Sen, Nirmalya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068611/
https://www.ncbi.nlm.nih.gov/pubmed/35508713
http://dx.doi.org/10.1038/s42003-022-03385-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068611/
https://www.ncbi.nlm.nih.gov/pubmed/35508713
http://dx.doi.org/10.1038/s42003-022-03385-x

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