The transcription factor complex LMO2/TAL1 regulates branching and endothelial cell migration in sprouting angiogenesis

The transcription factor complex, consisting of LMO2, TAL1 or LYL1, and GATA2, plays an important role in capillary sprouting by regulating VEGFR2, DLL4, and angiopoietin 2 in tip cells. Overexpression of the basic helix-loop-helix transcription factor LYL1 in transgenic mice results in shortened ta...

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Detalles Bibliográficos
Autores principales: Yamada, Yoshihiro, Zhong, Yi, Miki, Shiho, Taura, Akiko, Rabbitts, Terence H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068620/
https://www.ncbi.nlm.nih.gov/pubmed/35508511
http://dx.doi.org/10.1038/s41598-022-11297-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068620/
https://www.ncbi.nlm.nih.gov/pubmed/35508511
http://dx.doi.org/10.1038/s41598-022-11297-3

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