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Tumor microenvironment heterogeneity an important mediator of prostate cancer progression and therapeutic resistance
Prostate cancer is characterized by a high degree of heterogeneity, which poses a major challenge to precision therapy and drug development. In this review, we discuss how nongenetic factors contribute to heterogeneity of prostate cancer. We also discuss tumor heterogeneity and phenotypic switching...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068628/ https://www.ncbi.nlm.nih.gov/pubmed/35508696 http://dx.doi.org/10.1038/s41698-022-00272-w |