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Assignment of Ala, Ile, Leu(proS), Met, and Val(proS) methyl groups of the protruding domain of murine norovirus capsid protein VP1 using methyl–methyl NOEs, site directed mutagenesis, and pseudocontact shifts

The protruding domain (P-domain) of the murine norovirus (MNV) capsid protein VP1 is essential for infection. It mediates receptor binding and attachment of neutralizing antibodies. Protein NMR studies into interactions of the P-domain with ligands will yield insights not easily available from other...

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Detalles Bibliográficos
Autores principales: Maass, Thorben, Westermann, Leon Torben, Creutznacher, Robert, Mallagaray, Alvaro, Dülfer, Jasmin, Uetrecht, Charlotte, Peters, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068638/
https://www.ncbi.nlm.nih.gov/pubmed/35050443
http://dx.doi.org/10.1007/s12104-022-10066-7