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Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

Cofilin is best known for its ability to sever actin filaments and facilitate cytoskeletal recycling inside of cells, but at higher concentrations in vitro, cofilin stabilizes a more flexible, hyper-twisted state of actin known as “cofilactin”. While this filament state is well studied, a structural...

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Detalles Bibliográficos
Autores principales: Hylton, Ryan K., Heebner, Jessica E., Grillo, Michael A., Swulius, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068697/
https://www.ncbi.nlm.nih.gov/pubmed/35508487
http://dx.doi.org/10.1038/s41467-022-30116-x