Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

Ectopic ceramide accumulation in insulin-responsive tissues contributes to the development of obesity and impairs insulin sensitivity. Moreover, pharmacological inhibition of serine palmitoyl transferase (SPT), the first enzyme essential for ceramide biosynthesis using myriocin in rodents reduces bo...

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Detalles Bibliográficos
Autores principales: Li, Ying, Talbot, Chad Lamar, Chandravanshi, Bhawna, Ksiazek, Alec, Sood, Ayushi, Chowdhury, Kamrul Hasan, Maschek, J. Alan, Cox, James, Babu, Adhini Kuppuswamy Satheesh, Paz, Henry A., Babu, Pon Velayutham Anandh, Meyerholz, David K., Wankhade, Umesh D., Holland, William, Shyong Tai, E., Summers, Scott A., Chaurasia, Bhagirath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068713/
https://www.ncbi.nlm.nih.gov/pubmed/35508667
http://dx.doi.org/10.1038/s41598-022-11219-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068713/
https://www.ncbi.nlm.nih.gov/pubmed/35508667
http://dx.doi.org/10.1038/s41598-022-11219-3

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