Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination

Remyelination failure in multiple sclerosis (MS) contributes to progression of disability. The deficient repair results from neuroinflammation and deposition of inhibitors including chondroitin sulfate proteoglycans (CSPGs). Which CSPG member is repair-inhibitory or alters local inflammation to exac...

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Detalles Bibliográficos
Autores principales: Ghorbani, Samira, Jelinek, Emily, Jain, Rajiv, Buehner, Benjamin, Li, Cenxiao, Lozinski, Brian M., Sarkar, Susobhan, Kaushik, Deepak K., Dong, Yifei, Wight, Thomas N., Karimi-Abdolrezaee, Soheila, Schenk, Geert J., Strijbis, Eva M., Geurts, Jeroen, Zhang, Ping, Ling, Chang-Chun, Yong, V. Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068758/
https://www.ncbi.nlm.nih.gov/pubmed/35508608
http://dx.doi.org/10.1038/s41467-022-30032-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068758/
https://www.ncbi.nlm.nih.gov/pubmed/35508608
http://dx.doi.org/10.1038/s41467-022-30032-0

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