Recyclable cooperative catalyst for accelerated hydroaminomethylation of hindered amines in a continuous segmented flow reactor

Synthesis of hindered amines using the atom-efficient hydroaminomethylation (HAM) route remains a challenge. Here, we report a general and accelerated HAM in segmented flow, achieved via a cooperative effect between rhodium (Rh)/N-Xantphos and a co-catalyst (2-Fluoro-4-methylbenzoic acid) to increas...

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Detalles Bibliográficos
Autores principales: Ibrahim, Malek Y. S., Abolhasani, Milad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068773/
https://www.ncbi.nlm.nih.gov/pubmed/35508490
http://dx.doi.org/10.1038/s41467-022-30175-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068773/
https://www.ncbi.nlm.nih.gov/pubmed/35508490
http://dx.doi.org/10.1038/s41467-022-30175-0

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