Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF

Enhancer RNAs (eRNAs) are long non-coding RNAs that originate from enhancers. Although eRNA transcription is a canonical feature of activated enhancers, the molecular features required for eRNA function and the mechanism of how eRNAs impinge on target gene transcription have not been established. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gorbovytska, Vladyslava, Kim, Seung-Kyoon, Kuybu, Filiz, Götze, Michael, Um, Dahun, Kang, Keunsoo, Pittroff, Andreas, Brennecke, Theresia, Schneider, Lisa-Marie, Leitner, Alexander, Kim, Tae-Kyung, Kuhn, Claus-D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068813/
https://www.ncbi.nlm.nih.gov/pubmed/35508485
http://dx.doi.org/10.1038/s41467-022-29934-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068813/
https://www.ncbi.nlm.nih.gov/pubmed/35508485
http://dx.doi.org/10.1038/s41467-022-29934-w

Ejemplares similares