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Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966

Acutely, non-selective cannabinoid (CB) agonists have been shown to increase morphine antinociceptive effects, and we and others have also demonstrated that non-selective CB agonists attenuate morphine antinociceptive tolerance. Activation of cannabinoid CB2 receptors reverses allodynia and hyperalg...

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Detalles Bibliográficos
Autores principales: Reichenbach, Zachary W., DiMattio, Kelly, Rajakaruna, Suren, Ambrose, David, Cornwell, William D., Tallarida, Ronald J., Rogers, Thomas, Liu-Chen, Lee-Yuan, Tuma, Ronald F., Ward, Sara Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068870/
https://www.ncbi.nlm.nih.gov/pubmed/35529434
http://dx.doi.org/10.3389/fphar.2022.803331