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The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae

Arachidonic acid lipoxygenases (ALOXs) have been implicated in the immune response of mammals. The reaction specificity of these enzymes is decisive for their biological functions and ALOX classification is based on this enzyme property. Comparing the amino acid sequences and the functional properti...

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Detalles Bibliográficos
Autores principales: Heydeck, Dagmar, Reisch, Florian, Schäfer, Marjann, Kakularam, Kumar R., Roigas, Sophie A., Stehling, Sabine, Püschel, Gerhard P., Kuhn, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068934/
https://www.ncbi.nlm.nih.gov/pubmed/35531094
http://dx.doi.org/10.3389/fcell.2022.871585