Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-κB, AP-1, and JAK/STAT Inactivation

TMS-HDMF-5z is a hybrid of the natural products mosloflavone and resveratrol. It was discovered to show potent inhibitory effects against lipopolysaccharide (LPS)-induced production of inflammatory mediators in RAW 264.7 macrophages. However, its mechanism of action is unknown. Hence this study aime...

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Detalles Bibliográficos
Autores principales: Kim, Seo-Yeon, Hassan, Ahmed H.E., Chung, Kyung-Sook, Kim, Su-Yeon, Han, Hee-Soo, Lee, Hwi-Ho, Jung, Seang-Hwan, Lee, Kwang-Young, Shin, Ji-Sun, Jang, Eungyeong, Yoon, Seolmin, Lee, Yong Sup, Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068937/
https://www.ncbi.nlm.nih.gov/pubmed/35529447
http://dx.doi.org/10.3389/fphar.2022.857789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9068937/
https://www.ncbi.nlm.nih.gov/pubmed/35529447
http://dx.doi.org/10.3389/fphar.2022.857789

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