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Acute (R,S)-Ketamine Administration Induces Sex-Specific Behavioral Effects in Adolescent but Not Aged Mice

(R,S)-ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that was originally developed as an anesthetic. Most recently, (R,S)-ketamine has been used as a rapid-acting antidepressant, and we have reported that (R,S)-ketamine can also be a prophylactic against stress in adult mice. However...

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Detalles Bibliográficos
Autores principales: Mastrodonato, Alessia, Pavlova, Ina, Kee, Noelle, McGowan, Josephine C., Mann, J. John, Denny, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069103/
https://www.ncbi.nlm.nih.gov/pubmed/35527817
http://dx.doi.org/10.3389/fnins.2022.852010