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Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies

PURPOSE: Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early identification of IFN-AAB-positive patients for potential subsequent clinical interventions. METHODS: We an...

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Detalles Bibliográficos
Autores principales: Akbil, Bengisu, Meyer, Tim, Stubbemann, Paula, Thibeault, Charlotte, Staudacher, Olga, Niemeyer, Daniela, Jansen, Jenny, Mühlemann, Barbara, Doehn, Jan, Tabeling, Christoph, Nusshag, Christian, Hirzel, Cédric, Sanchez, David Sökler, Nieters, Alexandra, Lother, Achim, Duerschmied, Daniel, Schallner, Nils, Lieberum, Jan Nikolaus, August, Dietrich, Rieg, Siegbert, Falcone, Valeria, Hengel, Hartmut, Kölsch, Uwe, Unterwalder, Nadine, Hübner, Ralf-Harto, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Warnatz, Klaus, Spinetti, Thibaud, Schefold, Joerg C., Dörner, Thomas, Sander, Leif Erik, Corman, Victor M., Merle, Uta, Kurth, Florian, von Bernuth, Horst, Meisel, Christian, Goffinet, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069123/
https://www.ncbi.nlm.nih.gov/pubmed/35511314
http://dx.doi.org/10.1007/s10875-022-01252-2