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Copy number variation of urine exfoliated cells by low-coverage whole genome sequencing for diagnosis of prostate adenocarcinoma: a prospective cohort study

BACKGROUND: Non-invasive, especially the urine-based diagnosis of prostate cancer (PCa) remains challenging. Although prostate cancer antigen (PSA) is widely used in prostate cancer screening, the false positives may result in unnecessary invasive procedures. PSA elevated patients are triaged to fur...

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Detalles Bibliográficos
Autores principales: Guan, Youyan, Wang, Xiaobing, Guan, Kaopeng, Wang, Dong, Bi, Xingang, Xiao, Zhendong, Xiao, Zejun, Shan, Xingli, Hu, Linjun, Ma, Jianhui, Li, Changling, Zhang, Yong, Shou, Jianzhong, Wang, Baiyun, Qian, Ziliang, Xing, Nianzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069213/
https://www.ncbi.nlm.nih.gov/pubmed/35513884
http://dx.doi.org/10.1186/s12920-022-01253-5