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Optimal Treatment Selection in Sequential Systemic and Locoregional Therapy of Oropharyngeal Squamous Carcinomas: Deep Q-Learning With a Patient-Physician Digital Twin Dyad

BACKGROUND: Currently, selection of patients for sequential versus concurrent chemotherapy and radiation regimens lacks evidentiary support and it is based on locally optimal decisions for each step. OBJECTIVE: We aim to optimize the multistep treatment of patients with head and neck cancer and pred...

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Detalles Bibliográficos
Autores principales: Tardini, Elisa, Zhang, Xinhua, Canahuate, Guadalupe, Wentzel, Andrew, Mohamed, Abdallah S R, Van Dijk, Lisanne, Fuller, Clifton D, Marai, G Elisabeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069283/
https://www.ncbi.nlm.nih.gov/pubmed/35442211
http://dx.doi.org/10.2196/29455