Kill Two Birds with One Stone: A Multifunctional Dual‐Targeting Protein Drug to Overcome Imatinib Resistance in Philadelphia Chromosome‐Positive Leukemia

The Bcr/Abl plays a central role in Philadelphia chromosome‐positive (Ph+) leukemia because of the constitutively activated Abl tyrosine kinase and its downstream pathways. Currently, the clinical treatment of imatinib‐resistant patients with tyrosine kinase inhibitors is severely limited by drug re...

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Detalles Bibliográficos
Autores principales: Ma, Bohan, Feng, Hui, Feng, Chao, Liu, Yi, Zhang, Hailing, Wang, Jincheng, Wang, Wenjuan, He, Pengcheng, Niu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069375/
https://www.ncbi.nlm.nih.gov/pubmed/35239999
http://dx.doi.org/10.1002/advs.202104850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069375/
https://www.ncbi.nlm.nih.gov/pubmed/35239999
http://dx.doi.org/10.1002/advs.202104850

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