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Genome-wide analysis identify novel germline genetic variations in ADCY1 influencing platinum-based chemotherapy response in non-small cell lung cancer

To explore the pharmacogenomic markers that affect the platinum-based chemotherapy response in non-small-cell lung carcinoma (NSCLC), we performed a two-cohort of genome-wide association studies (GWAS), including 34 for WES-based and 433 for microarray-based analyses, as well as two independent vali...

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Detalles Bibliográficos
Autores principales: Mao, Chenxue, Chen, Juan, Zou, Ting, Zhou, Yuankang, Liu, Junyan, Li, Xi, Li, Xiangping, Li, Min, Pan, Pinhua, Zhuo, Wei, Gao, Yang, Hu, Shuo, Xiao, Desheng, Wu, Lin, Wang, Zhan, Xu, Heng, Yang, Wen, Xu, Yingjie, Xiao, Haihua, Hanada, Kazuhiko, Zhang, Wei, Zhou, Honghao, Yin, Jiye, Liu, Zhaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069400/
https://www.ncbi.nlm.nih.gov/pubmed/35530157
http://dx.doi.org/10.1016/j.apsb.2021.10.007