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Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis

Silicosis is a leading cause of occupational disease-related morbidity and mortality worldwide, but the molecular basis underlying its development remains unclear. An accumulating body of evidence supports gasdermin D (GSDMD)-mediated pyroptosis as a key component in the development of various pulmo...

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Detalles Bibliográficos
Autores principales: Song, Meiyue, Wang, Jiaxin, Sun, Youliang, Pang, Junling, Li, Xiaona, Liu, Yuan, Zhou, Yitian, Yang, Peiran, Fan, Tianhui, Liu, Ying, Li, Zhaoguo, Qi, Xianmei, Li, Baicun, Zhang, Xinri, Wang, Jing, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069405/
https://www.ncbi.nlm.nih.gov/pubmed/35530143
http://dx.doi.org/10.1016/j.apsb.2021.10.006