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An experimental medicine study of the effects of simvastatin on emotional processing, reward learning, verbal memory, and inflammation in healthy volunteers

RATIONALE: Clinical studies suggest that the highly lipophilic, anti-inflammatory molecule, simvastatin, might be an ideal candidate for drug repurposing in the treatment of depression. The neuropsychological effects of simvastatin are not known, but their ascertainment would have significant transl...

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Detalles Bibliográficos
Autores principales: De Giorgi, Riccardo, Quinton, Alice M. G., Waters, Shona, Cowen, Philip J., Harmer, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069418/
https://www.ncbi.nlm.nih.gov/pubmed/35511258
http://dx.doi.org/10.1007/s00213-022-06156-y