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Targeting β-catenin in acute myeloid leukaemia: past, present, and future perspectives

Acute myeloid leukaemia (AML) is an aggressive disease of the bone marrow with a poor prognosis. Evidence suggests long established chemotherapeutic regimens used to treat AML are reaching the limits of their efficacy, necessitating the urgent development of novel targeted therapies. Canonical Wnt s...

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Detalles Bibliográficos
Autores principales: Wagstaff, Megan, Coke, Brandon, Hodgkiss, Georgia R., Morgan, Rhys G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069440/
https://www.ncbi.nlm.nih.gov/pubmed/35352805
http://dx.doi.org/10.1042/BSR20211841