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Vertically sheathing laminar flow-based immunoassay using simultaneous diffusion-driven immune reactions

We present that enhanced simultaneous incubation of multiple antibodies (Abs) can be achieved by exploiting microfluidic laminar flows and difference in diffusivity between primary Ab (pAb) and secondary Ab (sAb). We demonstrate that injecting Ab of larger and smaller diffusivity (D(Ab)) in an upper...

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Detalles Bibliográficos
Autores principales: Kurmashev, Amanzhol, Kwon, Seyong, Park, Je-Kyun, Kang, Joo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069447/
https://www.ncbi.nlm.nih.gov/pubmed/35530621
http://dx.doi.org/10.1039/c9ra03855h