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Leukemia Stem Cell Frequency at Diagnosis Correlates With Measurable/Minimal Residual Disease and Impacts Survival in Adult Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogenous disease in which the initiation and maintenance of the malignant clone is blamed on a rare population of leukemia stem cells (LSCs). The persistence of such a malignant population is referred to as measurable/minimal residual disease (MRD). Evaluation o...

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Detalles Bibliográficos
Autores principales: Kamel, Azza M., Elsharkawy, Nahla M., Kandeel, Eman Z., Hanafi, Marwa, Samra, Mohammed, Osman, Randa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069678/
https://www.ncbi.nlm.nih.gov/pubmed/35530356
http://dx.doi.org/10.3389/fonc.2022.867684