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Molecular and cytological profiling of biological aging of mouse cochlear inner and outer hair cells

Age-related hearing loss (ARHL) negatively impacts quality of life in the elderly population. The prevalent cause of ARHL is loss of mechanosensitive cochlear hair cells (HCs). The molecular and cellular mechanisms of HC degeneration remain poorly understood. Using RNA-seq transcriptomic analyses of...

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Detalles Bibliográficos
Autores principales: Liu, Huizhan, Giffen, Kimberlee P., Chen, Lei, Henderson, Heidi J., Cao, Talia A., Kozeny, Grant A., Beisel, Kirk W., Li, Yi, He, David Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069708/
https://www.ncbi.nlm.nih.gov/pubmed/35417713
http://dx.doi.org/10.1016/j.celrep.2022.110665