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Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway
BACKGROUND: Interleukin-6 (IL-6) has been reported to be critical in oral squamous cell carcinoma (OSCC). However, the set of pathways that IL-6 might activate in OSCC are not fully understood. METHODS: IL-6 and Sox4 expressions were first determined with RT-qPCR, ELISA, Western blot, or immunohisto...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069786/ https://www.ncbi.nlm.nih.gov/pubmed/35513871 http://dx.doi.org/10.1186/s13046-022-02376-4 |