Cargando…

Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway

BACKGROUND: Interleukin-6 (IL-6) has been reported to be critical in oral squamous cell carcinoma (OSCC). However, the set of pathways that IL-6 might activate in OSCC are not fully understood. METHODS: IL-6 and Sox4 expressions were first determined with RT-qPCR, ELISA, Western blot, or immunohisto...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Li, Li, Xue, Cao, Peilin, Fei, Wei, Zhou, Hao, Tang, Na, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9069786/
https://www.ncbi.nlm.nih.gov/pubmed/35513871
http://dx.doi.org/10.1186/s13046-022-02376-4