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Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer’s Disease: Possible Therapeutic Role of K(V)1.3 Channel Blockade

Increase of deposits of amyloid β peptides in the extracellular matrix is landmark during Alzheimer’s Disease (AD) due to the imbalance in the production vs. clearance. This accumulation of amyloid β deposits triggers microglial activation. Microglia plays a dual role in AD, a protective role by cle...

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Detalles Bibliográficos
Autores principales: Revuelta, Miren, Urrutia, Janire, Villarroel, Alvaro, Casis, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070300/
https://www.ncbi.nlm.nih.gov/pubmed/35530176
http://dx.doi.org/10.3389/fncel.2022.868842