Construction of antifungal dual-target (SE, CYP51) pharmacophore models and the discovery of novel antifungal inhibitors

Fungal infections and drug-resistance are rapidly increasing with the deterioration of the external environment. Squalene cyclooxygenase (SE) and 14α-demethylase (CYP51) are considered to be important antifungal targets, and the corresponding pharmacophore models can be used to design and guide the...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Yue, Liu, Min, Wang, Jian, Ding, Zhuang, Sun, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070380/
https://www.ncbi.nlm.nih.gov/pubmed/35531010
http://dx.doi.org/10.1039/c9ra03713f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070380/
https://www.ncbi.nlm.nih.gov/pubmed/35531010
http://dx.doi.org/10.1039/c9ra03713f

Ejemplares similares