Increase in the apparent intercalation ability of a platinum complex via multivalency by installation into the sidechain of a graft copolymer and observation of structural changes in the intercalated DNA

Metal complexes with planar structures have been utilized as DNA intercalators that can be inserted into the base pairs of DNA strands, and have potential applications in DNA-targeting drug therapies. When designing the intercalator metal complexes, controlling their interactions with DNA is importa...

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Detalles Bibliográficos
Autores principales: Osawa, Shigehito, Takahashi, Riichi, Watanabe, Remi, Kubo, Sayaka, Otsuka, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070401/
https://www.ncbi.nlm.nih.gov/pubmed/35530992
http://dx.doi.org/10.1039/c9ra03485d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070401/
https://www.ncbi.nlm.nih.gov/pubmed/35530992
http://dx.doi.org/10.1039/c9ra03485d

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