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NR4A1 inhibits the epithelial–mesenchymal transition of hepatic stellate cells: Involvement of TGF-β–Smad2/3/4–ZEB signaling

This study aimed to examine whether nuclear receptor 4a1 (NR4A1) is involved in inhibiting hepatic stellate cell (HSC) activation and liver fibrosis through the epithelial–mesenchymal transition (EMT). HSC-T6 cells were divided into the control group, the acetaldehyde (200 μM, an EMT activator) grou...

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Detalles Bibliográficos
Autores principales: Huang, Qian, Xu, Jingying, Ge, Yanyan, Shi, Yue, Wang, Fei, Zhu, Mingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070444/
https://www.ncbi.nlm.nih.gov/pubmed/35600274
http://dx.doi.org/10.1515/biol-2022-0047