Cargando…

Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2)

Musashi 2 (MSI2) is an RNA binding protein (RBP) that regulates asymmetric cell division and cell fate decisions in normal and cancer stem cells. MSI2 appears to repress translation by binding to 3′ untranslated regions (3′UTRs) of mRNA, but the identity of functional targets remains unknown. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Karmakar, Shilpita, Ramirez, Oscar, Paul, Kiran V, Gupta, Abhishek K, Kumari, Vandana, Botti, Valentina, de los Mozos, Igor Ruiz, Neuenkirchen, Nils, Ross, Robert J, Karanicolas, John, Neugebauer, Karla M, Pillai, Manoj M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070473/
https://www.ncbi.nlm.nih.gov/pubmed/35528200
http://dx.doi.org/10.1093/narcan/zcac015