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A highly selective fluorescent probe for human NAD(P)H:quinone oxidoreductase 1 (hNQO1) detection and imaging in living tumor cells

Human NAD(P)H:quinone oxidoreductase (hNQO1) can be used as a biomarker for the early diagnosis of cancer. In this article, a novel fluorescent probe 1 for detecting hNQO1 was designed and synthesized by using 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) derivative (TCF-OH) as a...

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Detalles Bibliográficos
Autores principales: Zhu, Ya, Han, Jialing, Zhang, Qian, Zhao, Zhou, Wang, Jin, Xu, Xiaowei, Hao, Haiping, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070553/
https://www.ncbi.nlm.nih.gov/pubmed/35528556
http://dx.doi.org/10.1039/c9ra05650e