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Model Affitin and PEG modifications onto siRNA lipid nanocapsules: cell uptake and in vivo biodistribution improvements

Malignant melanoma is an aggressive tumor, associated with the presence of local and/or distant metastases. The development of gene therapy by the use of small interfering RNA (siRNA) represents a promising new treatment. However, the protection of this biomolecule is necessary in order for it to be...

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Detalles Bibliográficos
Autores principales: Resnier, Pauline, Lepeltier, Elise, Emina, Anthea Lucrezia, Galopin, Natacha, Bejaud, Jérôme, David, Stephanie, Ballet, Caroline, Benvegnu, Thierry, Pecorari, Frédéric, Chourpa, Igor, Benoit, Jean-Pierre, Passirani, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9070605/
https://www.ncbi.nlm.nih.gov/pubmed/35529231
http://dx.doi.org/10.1039/c9ra03668g